Ingelvac CircoFLEX® was the first in the FLEX Family of swine vaccines and the most revolutionary PCV2 vaccine on the market. As a result, it has built a reputation for providing safe, effective protection against porcine circovirus associated disease (PCVAD) from 1-shot around weaning.
Vaccine Overview
Single-dose, 1 mL vaccine approved for pigs 3 weeks of age or older.
Long duration of immunity Ingelvac CircoFLEX® provides at least 4 months of immunity, long enough to last through the critical grow-finish stage.
Rapid onset of immunity Unlike two-dose products, it provides effective immune response within 2 weeks after single dose vaccination.
Excellent safety profile Because it contains both Purified Circovirus Antigen (PCA™) and ImpranFLEX®, Ingelvac CircoFLEX® provides a strong immune response with low risk of injection site or other adverse reactions in pigs.
PCA™ and ImpranFLEX®
Ingelvac CircoFLEX® contains the unique combination of Purified Circovirus Antigen (PCA™) and ImpranFLEX®. PCA™ is the Ingelvac CircoFLEX® antigen where extraneous baculovirus from the virus-like particle (VLP) is removed, resulting in a highly refined vaccine.
ImpranFLEX® is a proprietary aqueous polymer adjuvant found in all FLEX Family™ vaccines. These two innovative vaccine technologies work together to generate a fast and long-lasting immune response and low risk of adverse reactions in vaccinated pigs.
Efficacy is the most important factor in the development of vaccines; however, we go further. With our customers and the health and wellbeing of their animals in mind we focus on creating vaccines that provide the pig performance you expect, minimize vaccination stress to the animal and can be conveniently administered by you.
This is why we developed ImpranFLEX® technology, an aqueous polymer adjuvant containing a matrix of crosslinked polymers that act like a sponge to the antigen. The antigens on the surface of the sponge-like matrix are released quickly whilst the sponge also releases antigen more slowly leading to a prolonged immune stimulus ImpranFLEX® is specifically designed to allow single dose, low volume vaccines with a fast onset of immunity and reliable protection all the way to slaughter.
By using this platform for various vaccines we bring you products which can be freshly mixed to further reduce vaccination stress for both you and your pigs without compromising safety or efficacy.
In Trial 1 and 2 Ingelvac CircoFLEX® was as safe as saline as measured by injection site lesions. The competitor vaccines induced a significantly greater amount of injection site lesions compared to Ingelvac CircoFLEX®.
REFERENCES
a Waddell.2012.IPVS.p935
b Sponheim.2012.Leman.p210
c Johnson.2013.AASV.p435-436
