M. hyopneumoniae control

Add to my reading list Remove from my reading list

M. hyopneumoniae control

M. hyopneumoniae control


The organism that causes enzootic pneumonia, Mycoplasma hyopneumoniae, attaches itself to the epithelial cells lining the upper respiratory tract. The cells colonize there, resulting in the destruction of cilia, the hair-like structures that help remove pathogens and foreign material from the lungs. In addition it elicits an inflammatory response and together with the impaired cleaning function it predisposes the lung to further infections and complicated pneumonia.



Mycoplasma hyopneumoniae is mainly transmitted by contact with affected, carrier pigs.

  • Animal to animal
  • Nasal secretions
  • Infection by airspread
  • Transmission possible by tools/equipment, boots, etc.
  • No transmission through sow milk or by insemination (boar semen)

Overcrowding, large group size, and poor air circulation can contribute to increased infection rates.



Clinical signs associated with Mycoplasma hyopneumoniae vary, depending on the presence of secondary infections with other bacteria or viruses. Normal signs of a simple infection include:

  • Deep, non-productive cough
  • Thumping
  • Mild to moderate fever
  • Rough coat
  • Decreased appetite/feed intake
  • Reduction in Average Daily Gain



Infection and clinical disease normally occur in the finishing phase of production, from 10- to 12-weeks of age to market. However, the infection can occur at any stage of production.

Seroconversion typically begins 2 to 4 weeks following infection. Serologic profiling can be used to identify the onset of infection and schedule appropriate vaccination timing.

Diagnosis of Mycoplasma hyopneumoniae is based on clinical signs and diagnostic testing.



Herd management practices can help reduce the severity of Mycoplasma hyopneumoniae in a population, but vaccination aids in prevention of the disease.



 1. Clark, L.K., Armstrong, C.H., Freeman, M.J., Scheidt, A.B., Sands-Freeman, L., Knox, K., 1991. Investigating the transmission of Mycoplasma hyopneumoniae in a swine herd with enzootic pneumonia. Veterinary Medicine 86:543-550.